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NHRMC Orthopedic Hospital

5301 Wrightsville Avenue • Wilmington, NC • 910-452-8100

NHRMC Orthopedic Hospital, formerly Cape Fear Hospital serves as New Hanover Regional Medical Center’s home for orthopedic services. The Orthopedic Hospital features designated orthopedic nurses, therapists, technicians and surgeons who are board-certified or eligible in orthopedic surgery. The center includes specialists in hand and shoulder, foot and ankle, and spine as well as arthroscopic surgeries, sports medicine and joint replacement.

The Orthopedic Hospital also offers a 24-hour emergency department, inpatient and outpatient surgery, respiratory therapy, rehabilitation medicine, diagnostic and imaging services, radiology services and laboratory services.


The NHRMC Orthopedic Hospital is located at 5301 Wrightsville Avenue in Wilmington, North Carolina. Click on a the red cross below for more map details and to get driving directions from your current location. Standard driving directions are also listed below the map.

View Cape Fear Hospital in a larger map

Driving Directions to New Hanover Regional Medical Center Orthopedic Hospital

Traveling East on US 74/76, US 17 or US 421 (From Lumberton, Whiteville, Myrtle Beach, Brunswick County, Clinton, etc.)

Enter Wilmington via the Cape Fear Memorial Bridge. Stay on US 17-74-76 (Dawson St.).  This will change its name to Oleander Dr. Continue straight on Oleander Dr. Once you cross Hwy. 132 (College Rd.), continue about 1.3 miles to Hawthorne Dr. Turn left and continue to Wrightsville Ave. Turn right. Look for Main Entrance signs. The Orthopedic Hospital will be on your left.

Traveling East on I-40 (From Raleigh, etc.) 

Enter Wilmington on I-40. It turns into Hwy. 132 (College Rd.). Stay on Hwy. 132 until you get to Wrightsville Ave. Turn left and stay on Wrightsville Ave. Look for Main Entrance signs.  Cape Fear Hospital will be about 1.4 miles on the left.

Traveling South on US 17 (From Jacksonville, Morehead City, etc.)

Enter Wilmington on US 17 (Market Street). Turn left on Military Cutoff Rd. This will change its name to Oleander Dr. Continue on Oleander Dr until you reach Hawthorne Dr.  Turn right and continue to Wrightsville Ave. Turn right. Look for Main Entrance signs. The Orthopedic Hospital will be on your left.

2131 S. 17th Street, Wilmington, NC 28401  |  910.343.7000