Dyshidrotic eczema is a condition in which small, itchy blisters develop on the hands and feet.

Dyshidrosis; Pompholyx

The cause is unknown. The condition seems to appear during certain times of the year.

Small fluid-filled blisters called vesicles appear on the hands and feet. They are most common along the edges of the fingers, toes, palms and soles. These blisters cause intense itching.

Scratching leads to skin changes and skin thickening. There may be cracks on the fingers or toes.

Large blisters may cause pain.

Your doctor may be able to diagnose this condition by simply looking at your skin.

Sometimes, a skin biopsy or skin scraping may be needed to rule out other causes such as a fungal infection.

• Anti-itch medicines taken by mouth (antihistamines)
• Moisturizers
• Strong steroid creams or ointments

Do not scratch the blisters. You should avoid frequent bathing and irritating substances, which can make itching worse.

Dyshidrotic eczema normally goes away without problems, but symptoms may later return. Excess scratching may lead to thick, irritated skin, which is more difficult to treat and takes longer to heal.

• Pain and itching that limits the use of the hands
• Secondary bacterial infection

Call your doctor if you have tenderness, redness, warmth, or fever, which may be signs of an infection. You should also call your doctor if you have any type of rash that does not go away with simple home treatments.

Behrman RE. Nelson Textbook of Pediatrics. 17th ed. Philadelphia, Pa: WB Saunders; 2004.

Habif TP. Clinical Dermatology. 4th ed. St. Louis, Mo: Mosby; 2004.